Name: INAHTA HTA Reports
Creator: ModernRelay

INAHTA HTA Reports

Health technology assessment reports from 120+ agencies worldwide (1989-present), evaluating whether drugs, medical devices, and therapies are clinically effective and cost-effective, with coverage recommendations and conclusions

HTA Reports Data

HTA Reports records
Record ID	Abstract	Authors	Conclusions	Country	Language	MeSH Terms	Methods	Objectives
1953229177	An English language summary is available	Paula Cantero Muñoz, Fátima Carmela Mori Gamarra, María del Carmen Maceira	The bibliographic search provided 506 references, of which 67 were read in full text, and 13 articles were selected for inclusion because they met the previously stablished inclusion criteria. To asse...	Spain	Spanish	Thyroid Nodule, Surgical Procedures, Operative, Ablation Techniques, Laser Therapy, Radiofrequency Ablation	A review of the scientific literature was carried out without time limitation until November 2018 in repositories of clinical practice guidelines (G-I-N, National Guideline Clearinghouse, SIGN), speci...	Assessing the safety and clinical effectiveness of thermal laser and radiofrequency ablation in the treatment of symptomatic benign solid TN compared to standard treatment (surgery or surveillance).
31995000000	An English language summary is available	Marshall D	a) No controlled trials of laparoscopic cholecystectomy comparing it with surgical cholecystectomy have been completed. However, it is being adopted at a rapid rate in Canadian hospitals; b) Total tre...	Canada	English, French	Cholecystectomy, Cholecystectomy, Laparoscopic, Cholelithiasis, Laparoscopy, Lithotripsy		testtest
31995000001	An English language summary is available	Comis J	a) The possible increased risk of infection with re-use is a concern; however, there is no conclusive evidence that there is no increased risk; b) Hospitals do not typically have guidelines as to the ...	Canada	English, French	Data Collection, Disposable Equipment, Equipment and Supplies, Hospital, Equipment Safety	Review	To address four issues related to the re-use of diagnostic cardiac catheters and angiography cardiac catheters: risk of infection, functional effectiveness, cost-effectiveness, and liability; request ...
31995000003	An English language summary is available	Comis J, Conlon J	a) Published cost-benefit and cost-effectiveness analyses of prenatal diagnosis for congenital anomalies focus on Down's syndrome and neural tube defects; b) Patau's syndrome, Edward's syndrome, hydro...	Canada	English, French	Prenatal Care	Bibliography	To ascertain the current state of knowledge regarding costs and benefits of prenatal screening programs.
31995000004	An English language summary is available	Menon D	a) There is a significant reduction in mortality for infants with signs or respiratory distress, who received the drug, averaging 5.7%. Pneumothorax, BPD and PDA are also significantly reduced with re...	Canada	English, French	Infant, Newborn, Diseases, Infant, Premature, Diseases, Intensive Care, Neonatal, Pulmonary Surfactants	Randomised controlled trial	To address the questions of cost, efficacy and appropriateness of use of Exosurf, and to examine mortality and long-term effects; request from provincial governments.
31995000005	An English language summary is available	Conlon J	a) Chiropractor applied manipulation was at least as effective in treating back pain as the alternative treatments used (in all but one study). It appears to be a safe treatment offering more immediat...	Canada	English, French	Back Pain, Chiropractic, Low Back Pain	Review	To undertake a literature review aimed at determining the current state of knowledge regarding the effectiveness and costs of chiropractic; requested by provincial governments.
31995000006	An English language summary is available	Comis J, To T	There is evidence that mammography screening reduces breast cancer mortality in women over 50. The evidence in younger women is still inconclusive	Canada	English, French	Breast Neoplasms, Mammography, Mass Screening	Review	To summarize findings reported by breast cancer screening studies, and to evaluate the impact of screening on incidence and mortality.
31995000007	An English language summary is available	Menon D, Sommerhalder S	a) 6 of 9 trials in which cost information was provided to physicians demonstrated changes in behaviour following this. At best, the effect was reported as transient; b) In all 5 trials in which clini...	Canada	English, French	Diagnostic Tests, Routine, Education, Medical, Practice Patterns, Physicians	Review	To review studies in which specific educational interventions were used as a means of changing physician behaviour; requested by provincial governments.
31995000008	An English language summary is available	Marshall, D	a) There is a divergence of opinion as to the best field strength for the highest patient throughput; b) Costs (all categories) increase with field strength; c) Radiologists believe that MR images pro...	Canada	English, French	Magnetic Resonance Imaging	Review	To examine MRI issues related to the magnetic field strength; requested by provincial governments.
31995000009	An English language summary is available	Canadian Coordinating Office for Health Technology Assessment	a) There is no scientifically acceptable evidence that chelation therapy is effective in treating heart disease, preventing repeat MI or death. Studies to date have been poorly designed, and are anecd...	Canada	English, French	Arteriosclerosis, Edetic Acid, Chelation Therapy	Review	Review the use of chelation for treating heart disease; requested by provincial governments.
31995000010	An English language summary is available	Canadian Coordinating Office for Health Technology Assessment	a)The ISIS-3 trial shows no difference in survival between streptokinase, tPA and ASPAC; the debate continues on optimal dosing and administration rates; b) The time between onset of symptoms of AMI a...	Canada	English, French	Anistreplase, Myocardial Infarction, Plasminogen Activators, Streptokinase, Tissue Plasminogen Activator, Urokinase-Type Plasminogen Activator, Fibrinolytic Agents	Review	To identify current controversies and emerging trends about thrombolytic therapy, and examine potential impact in Canada
31995000020	An English language summary is available	Espinas J, Borras J M, Granados A	Ambulatory surgery (AS) compared to inpatient surgery is a safe and cost-effective way of providing surgical services for a selected group of procedures on selected patients. Patient satisfaction with...	Spain	Catalan, English, Spanish	Laparoscopy, Length of Stay, Waiting Lists, Ambulatory Care	Review	To provide an overview of the current state of knowledge regarding the efficacy, safety, effectiveness and cost of this type of surgery. Structural, organizational and financial aspects are reviewed.
31995000021	An English language summary is available	Samprieto-Colom L, Almazan C, Granados A	Osteoporosis and its main clinical consequence, hip fracture, is a disorder associated with an important economic and social cost. This burden has recently increased the pressure to establish programs...	Spain	Catalan, English, Spanish	Absorptiometry, Photon, Bone Density, Estrogen Replacement Therapy, Hip Fractures, Menopause, Osteoporosis	Review	To provide an overview of the current state of scientific knowledge assessing the safety, efficacy and cost of bone densitometry (BD). Its impact on the prevention of osteoporotic fractures is assesse...
31995000022	An English language summary is available	Sampietro-Colom L, Granados A	There is no general agreement about: 1) the best combination of diagnostic technologies to use, and 2) the safety and efficacy of the different techniques used in epilepsy surgery. Nevertheless the on...	Spain	Catalan, English, Spanish	Epilepsy	Review	To provide an overview of the current state of scientific knowledge assessing the safety, efficacy, and related costs of epilepsy surgery. An assessment about the characteristics and amount of current...
31995000023	An English language summary is available	Pons JM	The most common radiosurgery techniques are gamma knife and linear accelerators. They are similar in relation to physical measurement and with regard to the complete response rate to the treatment and...	Spain	Catalan, English, Spanish	Arteriovenous Malformations, Brain Neoplasms, Neurosurgery, Radiosurgery	Review	To provide an overview of the current's state of scientific knowledge assessing the efficacy, safety, and cost of SR and the possible consequences of its introduction in Catalonia.
31995000024	An English language summary is available	Catalan Agency for Health Technology Assessment and Research	The utilization of lasers is associated with certain hazards (fire, chemical and biological hazards, tissue damage due to overexposure, etc.) that can affect both health professionals and patients. Th...	Spain	Catalan, English, Spanish	Consumer Product Safety, Equipment Safety, Laser Therapy, Lasers, Reference Standards, Safety	Review	To provide minimum standards of care for the safe use of lasers in health care facilities to prevent unnecessary exposure of professionals and patients to avoidable hazards associated with type III an...
31995000025	An English language summary is available	Samprieto-Colom L, Granados A	Laser therapy is a growing technology often associated with a decrease in the cost of the medical care and with a better recovery of the patient. Nevertheless, although in certain pathologies its cost...	Spain	Catalan, English, Spanish	Laser Therapy, Lasers	Review	To provide an overview about the meaning and resources required to establish a multidisciplinary laser therapy platform.
31995000026	An English language summary is available	Samprieto-Colom L, Granados A	Currently, there are two types of iodinated radiological contrast agents that differ, mainly, on its osmolality: high osmolality agents (conventional) and low osmolality agents (new). Both classes of ...	Spain	Catalan, English, Spanish	Contrast Media, Radiography	Review	To provide an overview about the benefits and costs of using two different low osmolar contrast utilization strategies (universal or selective). Literature review, information synthesis, and cost-bene...
31995000028	An English language summary is available	Samprieto-Colom L, Pons JM, Granados A	Although there are data suggesting the possible efficacy of excimer laser photorefractive keratectomy, there are no data indicating its long-term safety. The available data, mostly uncontrolled studie...	Spain	Catalan, English, Spanish	Keratotomy, Radial, Laser Therapy, Myopia, Photorefractive Keratectomy	Review	To provide an overview of the current's state of scientific knowledge assessing the safety, efficacy, and related costs of excimer laser photorefractive keratectomy. Other solid-state lasers for the s...
31995000029	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:There have been no scientific trials to assess the effectiveness of population bone screening. The predictive power of bone density screening is low. The effectiveness of HRT in preventing fr...	England	English	Absorptiometry, Photon, Bone Density, Estrogen Replacement Therapy, Hip Fractures, Mass Screening, Menopause, Osteoporosis	Systematic review	To assess whether a population-based screening programme for menopausal women with the aim of preventing fractures in elderly women should be established.
31995000030	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:There are very few well designed studies that assess the effectiveness of rehabilitation after stroke, and no studies that evaluate its cost-effectiveness. There is some evidence that formal ...	England	English	Cerebrovascular Disorders, Rehabilitation	Systematic review	To assess whether formal rehabilitation reduces disability and handicap and improves quality of life for people who have suffered a stroke.
31995000031	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:Assisted conception techniques may be relatively effective for most causes of subfertility with a maternity rate of around 12% per cycle. Surgery is not effective for women with severely dama...	England	English	Endometriosis, Fertilization in Vitro, Infertility, Infertility, Female, Infertility, Male, Insemination, Artificial, Pregnancy	Systematic review	To assess the effectiveness, resource implications, and management issues of treatments for subfertility.
31995000032	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical: Grommets and adenoidectomy, alone or in combination, are equally effective and reduce mean hearing impairment by less than 12 decibels. The clinical significance of small improvements is unc...	England	English	Adenoidectomy, Child Health Services, Hearing Disorders, Middle Ear Ventilation, Otitis Media with Effusion, Tonsillectomy	Systematic review	To assess whether surgical interventions are effective in combating disability from glue ear.
31995000033	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:Antidepressants are generally effective in the treatment of major depression but a significant number of patients drop out of treatment and many will relapse. The SSRI's are of similar effica...	England	English	Antidepressive Agents, Depression, Psychotherapy, Selective Serotonin Reuptake Inhibitors, Suicide	Systematic review	To assess which treatments are effective in the management of depression in primary care.
31995000034	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:Blood cholesterol by itself is a poor predictor of individual risk of CHD and other factors such as smoking, high blood pressure and ischaemic changes must be considered. Cholesterol lowering...	England	English	Cholesterol, Hypercholesterolemia, Mass Screening	Systematic review	To assess the role of cholesterol screening and cholesterol lowering treatment in reducing mortality from Coronary Heart Disease.

	Record ID	Abstract	Authors	Conclusions	Country	DOI	Language	MeSH Terms	Methods	Objectives	Project Status	Project URL	Publication Type	Publication Year	PubMed ID	Recommendations	Report URL	Source Organization	Title

Main30

HTA Reports Data

HTA Reports records
Record ID	Abstract	Authors	Conclusions	Country	Language	MeSH Terms	Methods	Objectives
1953229177	An English language summary is available	Paula Cantero Muñoz, Fátima Carmela Mori Gamarra, María del Carmen Maceira	The bibliographic search provided 506 references, of which 67 were read in full text, and 13 articles were selected for inclusion because they met the previously stablished inclusion criteria. To asse...	Spain	Spanish	Thyroid Nodule, Surgical Procedures, Operative, Ablation Techniques, Laser Therapy, Radiofrequency Ablation	A review of the scientific literature was carried out without time limitation until November 2018 in repositories of clinical practice guidelines (G-I-N, National Guideline Clearinghouse, SIGN), speci...	Assessing the safety and clinical effectiveness of thermal laser and radiofrequency ablation in the treatment of symptomatic benign solid TN compared to standard treatment (surgery or surveillance).
31995000000	An English language summary is available	Marshall D	a) No controlled trials of laparoscopic cholecystectomy comparing it with surgical cholecystectomy have been completed. However, it is being adopted at a rapid rate in Canadian hospitals; b) Total tre...	Canada	English, French	Cholecystectomy, Cholecystectomy, Laparoscopic, Cholelithiasis, Laparoscopy, Lithotripsy		testtest
31995000001	An English language summary is available	Comis J	a) The possible increased risk of infection with re-use is a concern; however, there is no conclusive evidence that there is no increased risk; b) Hospitals do not typically have guidelines as to the ...	Canada	English, French	Data Collection, Disposable Equipment, Equipment and Supplies, Hospital, Equipment Safety	Review	To address four issues related to the re-use of diagnostic cardiac catheters and angiography cardiac catheters: risk of infection, functional effectiveness, cost-effectiveness, and liability; request ...
31995000003	An English language summary is available	Comis J, Conlon J	a) Published cost-benefit and cost-effectiveness analyses of prenatal diagnosis for congenital anomalies focus on Down's syndrome and neural tube defects; b) Patau's syndrome, Edward's syndrome, hydro...	Canada	English, French	Prenatal Care	Bibliography	To ascertain the current state of knowledge regarding costs and benefits of prenatal screening programs.
31995000004	An English language summary is available	Menon D	a) There is a significant reduction in mortality for infants with signs or respiratory distress, who received the drug, averaging 5.7%. Pneumothorax, BPD and PDA are also significantly reduced with re...	Canada	English, French	Infant, Newborn, Diseases, Infant, Premature, Diseases, Intensive Care, Neonatal, Pulmonary Surfactants	Randomised controlled trial	To address the questions of cost, efficacy and appropriateness of use of Exosurf, and to examine mortality and long-term effects; request from provincial governments.
31995000005	An English language summary is available	Conlon J	a) Chiropractor applied manipulation was at least as effective in treating back pain as the alternative treatments used (in all but one study). It appears to be a safe treatment offering more immediat...	Canada	English, French	Back Pain, Chiropractic, Low Back Pain	Review	To undertake a literature review aimed at determining the current state of knowledge regarding the effectiveness and costs of chiropractic; requested by provincial governments.
31995000006	An English language summary is available	Comis J, To T	There is evidence that mammography screening reduces breast cancer mortality in women over 50. The evidence in younger women is still inconclusive	Canada	English, French	Breast Neoplasms, Mammography, Mass Screening	Review	To summarize findings reported by breast cancer screening studies, and to evaluate the impact of screening on incidence and mortality.
31995000007	An English language summary is available	Menon D, Sommerhalder S	a) 6 of 9 trials in which cost information was provided to physicians demonstrated changes in behaviour following this. At best, the effect was reported as transient; b) In all 5 trials in which clini...	Canada	English, French	Diagnostic Tests, Routine, Education, Medical, Practice Patterns, Physicians	Review	To review studies in which specific educational interventions were used as a means of changing physician behaviour; requested by provincial governments.
31995000008	An English language summary is available	Marshall, D	a) There is a divergence of opinion as to the best field strength for the highest patient throughput; b) Costs (all categories) increase with field strength; c) Radiologists believe that MR images pro...	Canada	English, French	Magnetic Resonance Imaging	Review	To examine MRI issues related to the magnetic field strength; requested by provincial governments.
31995000009	An English language summary is available	Canadian Coordinating Office for Health Technology Assessment	a) There is no scientifically acceptable evidence that chelation therapy is effective in treating heart disease, preventing repeat MI or death. Studies to date have been poorly designed, and are anecd...	Canada	English, French	Arteriosclerosis, Edetic Acid, Chelation Therapy	Review	Review the use of chelation for treating heart disease; requested by provincial governments.
31995000010	An English language summary is available	Canadian Coordinating Office for Health Technology Assessment	a)The ISIS-3 trial shows no difference in survival between streptokinase, tPA and ASPAC; the debate continues on optimal dosing and administration rates; b) The time between onset of symptoms of AMI a...	Canada	English, French	Anistreplase, Myocardial Infarction, Plasminogen Activators, Streptokinase, Tissue Plasminogen Activator, Urokinase-Type Plasminogen Activator, Fibrinolytic Agents	Review	To identify current controversies and emerging trends about thrombolytic therapy, and examine potential impact in Canada
31995000020	An English language summary is available	Espinas J, Borras J M, Granados A	Ambulatory surgery (AS) compared to inpatient surgery is a safe and cost-effective way of providing surgical services for a selected group of procedures on selected patients. Patient satisfaction with...	Spain	Catalan, English, Spanish	Laparoscopy, Length of Stay, Waiting Lists, Ambulatory Care	Review	To provide an overview of the current state of knowledge regarding the efficacy, safety, effectiveness and cost of this type of surgery. Structural, organizational and financial aspects are reviewed.
31995000021	An English language summary is available	Samprieto-Colom L, Almazan C, Granados A	Osteoporosis and its main clinical consequence, hip fracture, is a disorder associated with an important economic and social cost. This burden has recently increased the pressure to establish programs...	Spain	Catalan, English, Spanish	Absorptiometry, Photon, Bone Density, Estrogen Replacement Therapy, Hip Fractures, Menopause, Osteoporosis	Review	To provide an overview of the current state of scientific knowledge assessing the safety, efficacy and cost of bone densitometry (BD). Its impact on the prevention of osteoporotic fractures is assesse...
31995000022	An English language summary is available	Sampietro-Colom L, Granados A	There is no general agreement about: 1) the best combination of diagnostic technologies to use, and 2) the safety and efficacy of the different techniques used in epilepsy surgery. Nevertheless the on...	Spain	Catalan, English, Spanish	Epilepsy	Review	To provide an overview of the current state of scientific knowledge assessing the safety, efficacy, and related costs of epilepsy surgery. An assessment about the characteristics and amount of current...
31995000023	An English language summary is available	Pons JM	The most common radiosurgery techniques are gamma knife and linear accelerators. They are similar in relation to physical measurement and with regard to the complete response rate to the treatment and...	Spain	Catalan, English, Spanish	Arteriovenous Malformations, Brain Neoplasms, Neurosurgery, Radiosurgery	Review	To provide an overview of the current's state of scientific knowledge assessing the efficacy, safety, and cost of SR and the possible consequences of its introduction in Catalonia.
31995000024	An English language summary is available	Catalan Agency for Health Technology Assessment and Research	The utilization of lasers is associated with certain hazards (fire, chemical and biological hazards, tissue damage due to overexposure, etc.) that can affect both health professionals and patients. Th...	Spain	Catalan, English, Spanish	Consumer Product Safety, Equipment Safety, Laser Therapy, Lasers, Reference Standards, Safety	Review	To provide minimum standards of care for the safe use of lasers in health care facilities to prevent unnecessary exposure of professionals and patients to avoidable hazards associated with type III an...
31995000025	An English language summary is available	Samprieto-Colom L, Granados A	Laser therapy is a growing technology often associated with a decrease in the cost of the medical care and with a better recovery of the patient. Nevertheless, although in certain pathologies its cost...	Spain	Catalan, English, Spanish	Laser Therapy, Lasers	Review	To provide an overview about the meaning and resources required to establish a multidisciplinary laser therapy platform.
31995000026	An English language summary is available	Samprieto-Colom L, Granados A	Currently, there are two types of iodinated radiological contrast agents that differ, mainly, on its osmolality: high osmolality agents (conventional) and low osmolality agents (new). Both classes of ...	Spain	Catalan, English, Spanish	Contrast Media, Radiography	Review	To provide an overview about the benefits and costs of using two different low osmolar contrast utilization strategies (universal or selective). Literature review, information synthesis, and cost-bene...
31995000028	An English language summary is available	Samprieto-Colom L, Pons JM, Granados A	Although there are data suggesting the possible efficacy of excimer laser photorefractive keratectomy, there are no data indicating its long-term safety. The available data, mostly uncontrolled studie...	Spain	Catalan, English, Spanish	Keratotomy, Radial, Laser Therapy, Myopia, Photorefractive Keratectomy	Review	To provide an overview of the current's state of scientific knowledge assessing the safety, efficacy, and related costs of excimer laser photorefractive keratectomy. Other solid-state lasers for the s...
31995000029	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:There have been no scientific trials to assess the effectiveness of population bone screening. The predictive power of bone density screening is low. The effectiveness of HRT in preventing fr...	England	English	Absorptiometry, Photon, Bone Density, Estrogen Replacement Therapy, Hip Fractures, Mass Screening, Menopause, Osteoporosis	Systematic review	To assess whether a population-based screening programme for menopausal women with the aim of preventing fractures in elderly women should be established.
31995000030	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:There are very few well designed studies that assess the effectiveness of rehabilitation after stroke, and no studies that evaluate its cost-effectiveness. There is some evidence that formal ...	England	English	Cerebrovascular Disorders, Rehabilitation	Systematic review	To assess whether formal rehabilitation reduces disability and handicap and improves quality of life for people who have suffered a stroke.
31995000031	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:Assisted conception techniques may be relatively effective for most causes of subfertility with a maternity rate of around 12% per cycle. Surgery is not effective for women with severely dama...	England	English	Endometriosis, Fertilization in Vitro, Infertility, Infertility, Female, Infertility, Male, Insemination, Artificial, Pregnancy	Systematic review	To assess the effectiveness, resource implications, and management issues of treatments for subfertility.
31995000032	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical: Grommets and adenoidectomy, alone or in combination, are equally effective and reduce mean hearing impairment by less than 12 decibels. The clinical significance of small improvements is unc...	England	English	Adenoidectomy, Child Health Services, Hearing Disorders, Middle Ear Ventilation, Otitis Media with Effusion, Tonsillectomy	Systematic review	To assess whether surgical interventions are effective in combating disability from glue ear.
31995000033	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:Antidepressants are generally effective in the treatment of major depression but a significant number of patients drop out of treatment and many will relapse. The SSRI's are of similar effica...	England	English	Antidepressive Agents, Depression, Psychotherapy, Selective Serotonin Reuptake Inhibitors, Suicide	Systematic review	To assess which treatments are effective in the management of depression in primary care.
31995000034	An English language summary is available	NHS Centre for Reviews and Dissemination	Clinical:Blood cholesterol by itself is a poor predictor of individual risk of CHD and other factors such as smoking, high blood pressure and ischaemic changes must be considered. Cholesterol lowering...	England	English	Cholesterol, Hypercholesterolemia, Mass Screening	Systematic review	To assess the role of cholesterol screening and cholesterol lowering treatment in reducing mortality from Coronary Heart Disease.

	Record ID	Abstract	Authors	Conclusions	Country	DOI	Language	MeSH Terms	Methods	Objectives	Project Status	Project URL	Publication Type	Publication Year	PubMed ID	Recommendations	Report URL	Source Organization	Title

Main30