| EMEA-H-A-20-1530 |
| bupropion hydrochloride;naltrexone hydrochloride |
| A08AA |
| Human |
| Adverse event |
| https://www.ema.europa.eu/en/medicines/dhpc/mysimba |
| 2025-05-29 |
| 2026-01-16 |
| EMEA-H-A-31-1528 | hydroxyprogesterone caproate | Human | Post-authorisation measure | https://www.ema.europa.eu/en/medicines/dhpc/hydroxyprogesterone-caproate | 2024-07-17 | 2024-07-17 |
| EMEA/H-A20/1517/C/004214/0048; EMEA/H-A20/1517/C/005452/0003; EMEA/H-A20/1517/C/004085/0032; EMEA/H-A20/1517/C/004760/0017; EMEA/H-A20/1517/C/005113/0014 | abrocitinib;filgotinib;Baricitinib;upadacitinib;tofacitinib | D11AH08;L04AA45;L04AA37;L04AA44;L04AA29 | Human | Referral - Article 20 procedure | https://www.ema.europa.eu/en/medicines/dhpc/cibinqo-jyseleca-olumiant-rinvoq-xeljanz | 2023-02-21 | 2023-03-30 |
| EMEA/H/A-107i/1521 | Pholcodine | Human | Referral - Article 107i procedure | https://www.ema.europa.eu/en/medicines/dhpc/pholcodine | 2023-03-27 |
| EMEA/H/A-107i/1537 | metamizole | Human | Adverse event | https://www.ema.europa.eu/en/medicines/dhpc/metamizole-0 | 2024-12-03 | 2024-12-03 |
| EMEA/H/A-20/1489/C/2275/1489 | Ingenol mebutate | D06BX02 | Human | Interim measures;Referral - Article 20 procedure | https://www.ema.europa.eu/en/medicines/dhpc/picato | 2020-01-27 | 2020-02-14 |
| EMEA/H/A-20/1518/C/4272/0033 | Rucaparib camsylate | L01XX | Human | Referral - Article 20 procedure | https://www.ema.europa.eu/en/medicines/dhpc/rubraca-0 | 2022-05-05 | 2022-05-06 |
| EMEA/H/A-20/1525/C/4874/0013 | Crizanlizumab | B06AX01 | Human | Lack of effect;Referral - Article 20 procedure | https://www.ema.europa.eu/en/medicines/dhpc/adakveo-0 | 2023-06-15 | 2023-06-15 |
| EMEA/H/A-20/1538/C/004869/0014 | voxelotor | B06AX03 | Human | Referral - Article 20 procedure | https://www.ema.europa.eu/en/medicines/dhpc/oxbryta | 2024-10-07 | 2024-10-07 |
| EMEA/H/A-20/1540 | Chikungunya virus, strain CHIKV LR2006-OPY1, live attenuated | Human | Adverse event | https://www.ema.europa.eu/en/medicines/dhpc/ixchiq | 2025-05-22 | 2025-05-28 |
| EMEA/H/A-31/1481 | flucytosine | J02AX01 | Human | Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/flucytosine | 2020-06-04 | 2020-06-04 |
| EMEA/H/A-31/1482 | estradiol | G03CA03 | Human | Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/estradiol | 2020-02-20 | 2020-02-20 |
| EMEA/H/A-31/1486 | leuprorelin | Human | Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/leuprorelin | 2020-10-02 |
| EMEA/H/A-31/1488 | cyproterone | Human | Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/cyproterone | 2020-04-29 |
| EMEA/H/A-31/1496 | ulipristal acetate | Human | Interim measures | https://www.ema.europa.eu/en/medicines/dhpc/esmya-ulipristal-acetate-gedeon-richter | 2020-03-23 | 2020-03-23 |
| EMEA/H/A-31/1501 | amfepramone | A08AA03 | Human | Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/amfepramone | 2023-02-08 | 2023-02-08 |
| EMEA/H/A-31/1510 | nomegestrol;chlormadinone | G03 | Human | Adverse event;Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/zoely | 2022-11-08 | 2022-11-08 |
| EMEA/H/A-31/1514 | terlipressin | H01BA04 | Human | Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/terlipressin | 2022-12-01 | 2023-02-17 |
| EMEA/H/A-31/1520 | topiramate;phentermine | N03AX11 | Human | Restriction of indication | https://www.ema.europa.eu/en/medicines/dhpc/topiramate-phentermine | 2023-11-01 | 2023-11-21 |
| EMEA/H/A-31/1526 | pseudoephedrine | R01BA02 | Human | Referral - Article 31 | https://www.ema.europa.eu/en/medicines/dhpc/pseudoephedrine | 2024-02-09 | 2024-02-08 |
| EMEA/H/A-31/1539 | Finasteride;dutasteride | Human | Post-authorisation measure | https://www.ema.europa.eu/en/medicines/dhpc/finasteride-dutasteride | 2025-09-12 | 2025-10-07 |
| EMEA/H/C/000074 | eptacog alfa (activated) | B02BD08 | Human | Medicine shortage;Quality defect | https://www.ema.europa.eu/en/medicines/dhpc/novoseven | 2024-08-19 | 2024-08-19 |
Procedure Number | Active Substances | ATC Code (Human) | ATCvet Code (Veterinary) | Category | DHPC Type | DHPC URL | Dissemination Date | First Published Date | Last Updated Date | Name of Medicine | Other Related Medicines (Nationally Authorised) | Referral Name | Regulatory Outcome | Species | Therapeutic Area (MeSH) |
|---|